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【Vapourtec】Application Note 7 – Ester Hydrolysis

Example: Flow-Through Ester Hydrolysis under Superheated Conditions

This Application Note illustrates how the R-2 pump/injector and R-4 flow reactor modules can be readily used to perform flow-through chemistry under superheated conditions.

In this example, performing the simple ester hydrolysis of the ethyl ester 1 to the benzoic acid 2 under superheated conditions is shown to increase throughput and/or reduce the reaction time.

 

Setup:

 

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