Oxidation Using a Gas-Liquid Membrane Reactor
This application note illustrates the use of the Vapourtec R-Series system with gas- liquid “tube-in-tube” reactor to perform in flow an oxidation previously shown in batch in the publication
“Transition-Metal free approach to efficient aerobic oxidation of alcohols to aldehydes and ketones under mild conditions” (see “Reference Publication”, below)
In that study, TEMPO acts as the key oxidizing ingredient, NaNO₂ as a recyclable oxygen activator and oxygen as the terminal oxidant. This green and sustainable process has been optimized out of the TEMPO/Br₂/NaNO₂ system and resulted in HCl and HBr as cheap and readily available Br₂ alternatives. The general methodology comprises a reaction under ambient air and temperature, with CH₂Cl₂ as solvent and reaction times of approximately 10 hours.
| 產品型錄
Vapourtec 產品型錄下載
【Vapourtec】官網
