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【Vapourtec】Application Note 23 – SNAr with dimethylamine

Reaction Optimization and Scale-Up of a SNAr Reaction with a Volatile Dissolved Gas

This example illustrates the use of the Vapourtec R-Series system to react dissolved gases under pressure without the use of scale limiting pressure reactors (e.g. Parr ‘bombs’). The SnAr displacement of an aryl fluoride with dimethylamine is described.

 

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