This example illustrates the use of the new Vapourtec tube in tube gas reactor combined with the Vapourtec R-Series system to react reagent gases under pressure without the use of scale limiting pressure reactors (e.g. Parr ‘bombs’).

Nitration with fuming nitric acid and subsequent scale-up
This Application Note illustrates how a Vapourtec acid resistant R Series flow chemistry system

Reduction of aromatic nitro compounds with iron is a facile way to convert an aromatic nitro group to the corresponding amino group in the presence of an aryl halide.

This application note illustrates ease of scale-up and ease of control of a reaction that in batch would require careful incremental addition of reagents.

α-Bromination of ketones is an important reaction in organic synthesis as the resulting α-Bromo- ketones are widely used in organic synthesis as valuable reaction intermediates used in the synthesis of variety of biologically active compounds.

Alkylation of 2-Oxo-cyclopentanecarboxylic acid ethyl ester under biphasic conditions using phase transfer catalysis

This example illustrates use of a heterogeneous catalyst to perform a Suzuki coupling with high conversion and short residence times.

This application note illustrates how a reaction which would be subject to thermal runaways and possible explosions in batch mode can be carried out safely using a continuous flow approach.

Array Synthesis using Loop Injection and a Tubing Reactor Combined with a Scavenger Column