Simplified Aromatic Nitro Reduction in the Presence of an Aryl Halide
Reduction of aromatic nitro compounds with iron is a facile way to convert an aromatic nitro group to the corresponding amino group in the presence of an aryl halide. 15-20 g of the above compound was required for an array template, and although refluxing the nitro compound in water:ethanol (3:1, v/v) in the presence of iron and ammonium chloride gave good conversion to desired product, removal of the iron oxide and ammonium salts proved to be difficult, and yields were 70% at best.
Introduction:
This study demonstrates a flow based approach to reduction of an aromatic nitro compounds using a column of iron granules as the catalyst.
Setup:
| 產品型錄
Vapourtec 產品型錄下載
【Vapourtec】官網
